Eyewire Today http://eyewiretoday.com/ Eyewire Today en-us Sat, 13 Feb 2016 20:15:41 GMT Sat, 13 Feb 2016 20:15:41 GMT EyewireToday.com Research Consortium Identifies Key Piece in Parkinson's Disease Pathology http://eyewiretoday.com/view.asp?url=20160129-research_consortium_identifies_key_piece_in_parkinsons_disease_pathology An international public-private research consortium has identified and validated a cellular role of a primary Parkinson's disease drug target: the LRRK2 kinase. Published in the open-access eLife journal (http://dx.doi.org/10.7554/eLife.12813), the f... Fri, 29 Jan 2016 18:27:00 GMT High Levels of Urate in Blood Associated with Lower Risk of Parkinson’s Disease http://eyewiretoday.com/view.asp?url=20160114-high_levels_of_urate_in_blood_associated_with_lower_risk_of_parkinsons_disease Men who have high levels of urate in their blood may be less likely to develop Parkinsons disease, according to a study published in Neurology (January 13). Urate is formed when purines are broken down in the body. The study evaluated 90,214 particip... Thu, 14 Jan 2016 18:45:00 GMT Blocking Inflammation Shown to Slow Alzheimer’s Development http://eyewiretoday.com/view.asp?url=20160111-blocking_inflammation_shown_to_slow_alzheimers_development Blocking inflammation in the brain may slow the progression of Alzheimers disease (AD), according to a new study published in Brain (January 6). To understand migroglial proliferation in AD and the potential efficacy of inhibiting the colony-stimulat... Mon, 11 Jan 2016 19:38:00 GMT Estriol Combined with Glatiramer Acetate Found Effective for Women with Relapsing-Remitting MS http://eyewiretoday.com/view.asp?url=20160107-estriol_combined_with_glatiramer_acetate_found_effective_for_women_with_relapsing-remitting_ms Estriol plus glatiramer acetate may reduce relapse rates in women with relapsing-remitting multiple sclerosis (MS), new findings indicate. Noting that preclinical studies have shown that estriol treatment is anti-inflammatory and neuroprotective, the... Thu, 7 Jan 2016 15:47:00 GMT Hepatitis C Associated with Increased Risk of Parkinson’s Disease http://eyewiretoday.com/view.asp?url=20160105-hepatitis_c_associated_with_increased_risk_of_parkinsons_disease The hepatitis C virus may be associated with an increased risk of developing Parkinsons disease, according to new data published in Neurology. In the Taiwanese study, investigators placed participants with hepatitis into three groupsthose infected wi... Tue, 5 Jan 2016 19:05:00 GMT NeuroDerm Starts Patient Enrollment in Phase II Trial of ND0612H for Advanced Parkinson’s Disease http://eyewiretoday.com/view.asp?url=20151230-neuroderm_starts_patient_enrollment_in_phase_ii_trial_of_nd0612h_for_advanced_parkinsons_disease NeuroDerm Ltd. announced the start of patient enrollment in a first efficacy trial of ND0612H, the company's continuously administered subcutaneous levodopa/carbidopa solution. This treatment is intended to be an alternative to current treatments for... Wed, 30 Dec 2015 15:07:00 GMT Study to Test Effectiveness of App to Track Concussions http://eyewiretoday.com/view.asp?url=20151215-study_to_test_effectiveness_of_app_to_track_concussions Researchers at NYU Langone Medical Center will begin testing whether a new free mobile app for iPhone and Apple Watch can help those with concussions better track their symptoms during the critical six weeks following their diagnosis. The ResearchKit... Tue, 15 Dec 2015 18:21:00 GMT Ischemic Stroke Risk in Young Adults More Pronounced in African Americans http://eyewiretoday.com/view.asp?url=20151209-ischemic_stroke_risk_in_young_adults_more_pronounced_in_african_americans New findings suggest pronounced ethnic differences in ischemic stroke subtypes in young adults. In a new study published in BMC Neurology (October 29, 2015), authors conducted a population-based study controlling for age and sex, finding that African... Wed, 9 Dec 2015 16:48:00 GMT Adverse Events and Use of Healthcare Resources More Prevalent Among Those Not Using Rescue Medications for Seizure Clusters http://eyewiretoday.com/view.asp?url=20151208-adverse_events_and_use_of_healthcare_resources_more_prevalent_among_those_not_using_rescue_medications_for_seizure_clusters New data presented at the Annual Meeting of American Epilepsy Society Annual Meeting found there were more adverse outcomes and greater use of healthcare resources among those who did not always use a rescue medication to treat seizure clusters, comp... Tue, 8 Dec 2015 16:43:00 GMT Neural Stem Cells Found to Promote Remyelination http://eyewiretoday.com/view.asp?url=20151123-neural_stem_cells_found_to_promote_remyelination Endogenous neural stem cells might offer a new therapeutic avenue for the treatment of demyelinating disorders such as MS, according to a new study published in Nature (October 15, 2015). Specifically, the authors looked at a subset of adult neural s... Mon, 23 Nov 2015 17:33:00 GMT Gene Discovered to Play a Role in Development of MS http://eyewiretoday.com/view.asp?url=20151123-gene_discovered_to_play_a_role_in_development_of_ms New findings point to a role for FAM126A (also known as hyccin) in supporting myelination, an important process in development and also following acute exacerbations in multiple sclerosis (Nature Cell Biology, Nov 16). FAM126A is a leukodystrophy pro... Mon, 23 Nov 2015 17:33:00 GMT Decreased Sense of Smell Tied to Alzheimer’s Disease http://eyewiretoday.com/view.asp?url=20151118-decreased_sense_of_smell_tied_to_alzheimers_disease A decreased sense of smell could be an early symptom of Alzheimers disease, new findings suggest. In a study recently published in JAMA Neurology (November 16), researchers administered the Brief Smell Identification Test (B-SIT) in 1,630 participant... Wed, 18 Nov 2015 20:29:00 GMT CSF Biomarkers Increased in Parkinson’s Disease http://eyewiretoday.com/view.asp?url=20151106-csf_biomarkers_increased_in_parkinsons_disease In a cross-sectional analysis published in Neurology, researchers analyzed CSF samples in 38 elderly controls and 100 patients with Parkinson's disease (82 without dementia and 18 with dementia) from the prospective Swedish BioFinder study. Specifica... Fri, 6 Nov 2015 17:59:00 GMT Stressful Occupations May Increase Risk of Stroke http://eyewiretoday.com/view.asp?url=20151020-stressful_occupations_may_increase_risk_of_stroke High strain jobs are associated with an increased risk of stroke, particularly in women, new findings suggest. In a meta-analysis published in Neurology (October 14), researchers searched various medical databases for prospective cohort studies with ... Tue, 20 Oct 2015 18:30:00 GMT First US Patients Treated with Focused Ultrasound for Parkinson’s-Related Dyskinesia http://eyewiretoday.com/view.asp?url=20150902-first_us_patients_treated_with_focused_ultrasound_for_parkinsons-related_dyskinesia Researchers at the University of Maryland and the University of Virginia have performed the first focused ultrasound treatments in the United States for dyskinesia associated with Parkinsons disease. These treatments are part of international pilot s... Wed, 2 Sep 2015 16:07:00 GMT No Good Evidence to Support OTC Antioxidants in MS http://eyewiretoday.com/view.asp?url=20150824-no_good_evidence_to_support_otc_antioxidants_in_ms There is no clinical evidence to support recommendation of OTC antioxidant compounds for patients with MS, a new analysis shows. (Mult Scler., epub) However, preclinical evidence is potentially promising for epigallocatechin-3-gallate (ECGC) and (alp... Mon, 24 Aug 2015 21:11:00 GMT Evidence of Disease Activity in MS a Possible Marker of Treatment Effect http://eyewiretoday.com/view.asp?url=20150824-evidence_of_disease_activity_in_ms_a_possible_marker_of_treatment_effect RRMS patients who use more first line and less second line disease modifying treatment may be more like to show evidence of disease activity (EDA) compared to others with the disease, a new study suggests. (PLoS One, e-pub) In fact, at one year follo... Mon, 24 Aug 2015 21:08:00 GMT Small Bowel Feeding Bests Gastric Feeding For Severe TBI, New Analysis Finds http://eyewiretoday.com/view.asp?url=20150624-small_bowel_feeding_bests_gastric_feeding_for_severe_tbi_new_analysis_finds While there is no consensus for the preferred route of feeding following severe traumatic brain injury (TBI), new evidence suggests that small bowel feeding might be the preferred method over gastric feeding. Writing in the Journal of Neurosurgery, r... Wed, 24 Jun 2015 14:11:00 GMT NeuroDerm Poster Selected for Blue Ribbon Highlights Session: International Congress of Parkinson's Disease and Movement Disorders Annual Meeting http://eyewiretoday.com/view.asp?url=20150619-neuroderm_poster_selected_for_blue_ribbon_highlights_session_international_congress_of_parkinsons_disease_and_movement_disorders_annual_meeting NeuroDerm Ltd's poster presentation, "Stable levodopa plasma levels with ND0612 (LD/CDfor subcutaneous infusion) in Parkinson's disease (PD) patients with motor fluctuations" was part of the 19th International Congress of Parkinson's Disease and Mov... Fri, 19 Jun 2015 13:33:00 GMT Tool May Help MS Patients Assess Voice Quality http://eyewiretoday.com/view.asp?url=20150522-tool_may_help_ms_patients_assess_voice_quality The Voice Handicap Index (VHI) is an effective tool to assess patient self-perception of voice quality among MS patients (Int Arch Otorhinolaryngol. 2015 Apr;19(2):100-5). However, researchers showed that it may not reflect the severity of dysphonia ... Fri, 22 May 2015 15:55:00 GMT SWI Shows Promise for In-Vivo Study of EAE and MS http://eyewiretoday.com/view.asp?url=20150522-swi_shows_promise_for_in-vivo_study_of_eae_and_ms Researchers may be closer to using susceptibility-weighted imaging (SWI) to investigate the contribution of vascular-based hypointensities in experimental autoimmune encephalomyelitis (EAE) model of multiple sclerosis (MS) over time. (PLoS One. 2015 ... Fri, 22 May 2015 15:36:00 GMT Most Women Don't Know Female-Specific Signs, Symptoms of Stroke http://eyewiretoday.com/view.asp?url=20150427-most_women_dont_know_female-specific_signs_symptoms_of_stroke A new survey shows that most women dont know the risks or symptoms females face when it comes to having a stroke.The survey of 1,000 women, compiled by researchers at The Ohio State University Wexner Medical Center, found that only 11 percent of wom... Mon, 27 Apr 2015 14:49:00 GMT Biogen Idec Reports Positive Top-Line Results From Phase 2 Anti-Lingo-1 Trial In People With Acute Optic Neuritis http://eyewiretoday.com/view.asp?url=20150108-biogen_idec_reports_positive_top-line_results_from_phase_2_anti-lingo-1_trial_in_people_with_acute_optic_neuritis Biogen Idec (NASDAQ: BIIB) today announced top-line results from the Phase 2 acute optic neuritis (AON) RENEW trial in which treatment with anti-LINGO-1 showed evidence of biological repair of the visual system. Anti-LINGO-1 demonstrated an improveme... Thu, 8 Jan 2015 14:33:00 GMT NeuroDerm: Phase IIa Data for SC levodopa/carbidopa Promising http://eyewiretoday.com/view.asp?url=20141230-neuroderm_phase_iia_data_for_sc_levodopacarbidopa_promising Continuous, subcutaneous delivery of NeuroDerm Ltd.'s proprietary liquid levodopa/carbidopa (LD/CD) product candidates, ND0612H and ND0612L, led to clinically-significant plasma levodopa levels, the company says. The results, they say, suggest that t... Tue, 30 Dec 2014 13:41:00 GMT Athena Diagnostics to Present Original Research on Neurogenetics at American Academy of Neurology's 2014 Annual Meeting http://eyewiretoday.com/view.asp?url=20140501-athena_diagnostics_to_present_original_research_on_neurogenetics_at_american_academy_of_neurologys_2014_annual_meeting Quest Diagnostics (NYSE: DGX), the world's leading provider of diagnostic information services, today announced that several scientists from its Athena Diagnostics specialty neurology business will present research during the the American Academy of ... Thu, 1 May 2014 18:44:00 GMT