First US Patients Treated With Accelerated Cross-linking

• Share
• E-mail
• Print

The American-European Congress of Ophthalmic Surgery (ACOS) and Avedro, Inc., jointly announced that the first patients have been treated in an ACOS study of accelerated corneal collagen cross-linking (CXL) utilizing Avedro’s KXL System. Patients with keratoconus were treated at the Slade and Baker Vision Center in Houston, Texas, by Stephen Slade, MD, and Greg Parkhurst, MD. The ACOS study is a phase 3, multicenter, randomized, controlled evaluation to study accelerated CXL in eyes with keratoconus or corneal ectasia after refractive surgery. ACOS is sponsoring the study, which will be conducted in up to 100 clinical centers across the United States.

Each of the clinical sites will exclusively use Avedro’s KXL System and proprietary riboflavin for accelerated CXL.

“I am extremely honored to be able to treat the first patients in the US ACOS CXL trial. This will be the largest trial of cross-linking to date in the United States, and will use the latest equipment,” Dr. Slade said in a news release. “The idea of stopping a blinding eye disease with this very gentle technology is most gratifying to me as a corneal surgeon. I could not be more pleased for my patients.”

Clinical sites that have installed Avedro’s equipment are now recruiting eligible patients with keratoconic and post-LASIK ectasia for treatment. A list of clinical sites is available at www.nkcf.org.

The KXL system for accelerated CXL has received the CE Mark and is commercially available in 58 countries outside the United States.

Click here for more industry news and clinical trial updates.

Comment on this Article:

You must be logged in to leave a comment.

TOP 5 ARTICLES FROM 2012

• When My Time for Cataract Surgery Comes

  Five surgeons were asked to choose an IOL for their own cataract procedure and explain the rationale for their choices.

  By Neiel Baronberg, MD; Steven J. Dell, MD; Mark Packer, MD, CPI; Audrey R. Talley-Rostov, MD; and Robert J. Cionni, MD

• Presbyopia Update 2012: New Technologies and Novel Treatments

  By Mitchell C. Shultz, MD

• Piggyback IOLs for Residual Refractive Error After Cataract Surgery

  An overview of the indications, contraindications, surgical technique, and complications.

  By Jonathan B. Rubenstein, MD

• How to Get the Most out of Three Premium IOLs

  By Elizabeth A. Davis, MD; Eric D. Donnenfeld, MD; Allon Barsam, MD; and Christopher E. Starr, MD

• Cataract Surgery Complication Rates: How Are We Doing?

  The femtosecond laser has the potential to improve cataract surgical outcomes and reduce complications, but studies must test this hypothesis.

  By David F. Chang, MD