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In This Issue:

TECHNIQUES

Conquering the Last Frontier of Interventional Cardiology Top 5 Viewed Strategies and tools for facing coronary artery chronic total occlusions. By Rajesh M. Dave, MD, FACC, FSCAI

TIPS & TRICKS

Technique for Crossing and Covering the Carina of a Bifurcation Coronary Artery Lesion By David G. Rizik, MD, FACC, FSCAI

COVER STORY

Percutaneous Aortic Valve Replacement Top 5 Viewed An update on the current state of the CoreValve device. By Eberhard Grube, MD, and Dinesh Nair, MD

Percutaneous Aortic Valve Replacement Top 5 Viewed An update on the current state of the Sapien percutaneous aortic valve. By Augusto Pichard, MD, and Lowell Satler, MD

Transapical Aortic Valve Implantation An alternative for high-risk patients with aortic stenosis? By S. Chris Malaisrie, MD, and Patrick M. McCarthy, MD

Mitral Valve Repair Using the MitraClip: From Concept to Reality Top 5 Viewed Early experience with the MitraClip device suggests that it may be a viable therapeutic option in selected patients with MR. By Saibal Kar, MD, FACC, FAHA, FSCAI; Ted E. Feldman, MD, FSCAI; and Frederick St. Goar, MD, FACC, FSCAI

Coronary Sinus and Direct Annuloplasty Approaches for Percutaneous Mitral Valve Repair With device design improvements, proper patient selection, and careful technique, percutaneous coronary sinus annuloplasty may be a viable treatment option for mitral regurgitation. By Alec Vahanian, MD

Current PFO and Migraine Trials With the recent troubles concerning MIST, where do we go from here? By Brian Whisenant, MD

Patent Foramen Ovale Closure for Cryptogenic Stroke Developing a treatment strategy guided by clinical data. By HoHai Van, MD, and Jonathan Tobis, MD

Percutaneous Treatment for FMR: A Ventricular Approach Transpericardial LV chamber and annulus remodeling for mitral regurgitation with the iCoapsys System. By Wes R. Pedersen, MD, and Ted E. Feldman, MD, FSCAI

Dynamic Imaging for Structural Heart Disease Interventions Why three-dimensional image guidance is important in structural cardiac interventions. By John D. Carroll, MD

Atrial Transseptal Puncture Techniques Top 5 Viewed Atrial transseptal puncture is increasingly important for cardiac interventions and has undergone recent technical advances. By T.R.D. Shaw, MD, FRCP, FESC

An Interview With Frank T. Bunch, MD An expert in coronary and peripheral interventions talks about training on the early atherectomy devices, the coronary skills he applies in peripheral interventions, and what's on the coronary frontier. By Frank T. Bunch, MD

Structural and Valvular Update By Ted E. Feldman, MD, FSCAI, Chief Medical Editor